基因治疗的病毒载体

缝匠病毒载体平台

Single-Use Technologies and Associated 服务 to Address the 过程 Development and Productions Needs of Manufacturers of Viral Vectors

Sartorius technologies are ideally suited for the production of viral vaccines, 载体和基因治疗. 他们允许的端到端, single-use processing of viruses from process development through to commercial manufacturing at the 2000 L-scale. Manufacturers of virus-related products are benefiting from our unique upstream and downstream technologies, analytics and services including our process development consultancy, cost modelling and process engineering capabilities.

Gene therapy has become one of the most rapidly evolving and promising fields in regenerative medicine and has a wide range of potential applications, such as the treatment of hereditary genetic disorders, 癌症和传染病. Gene therapy mainly encompasses the use of a viral vector to introduce an intact gene, either directly into the patient (in vivo) or indirectly via transduction of cells before infusion into the patient (ex vivo), to reconstitute or modify a harmful gene variant.

The growing number of viral vectors used as clinical therapeutics will require scalable commercial upstream and downstream processes to be developed and optimized to ensure that critical quality attributes (CQAs) are retained.

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Panel Discussion: CAR-T 细胞疗法 for Cancer Treatment

Experts share insights and perspectives on where the cellular immunotherapy industry is headed.

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pDNA生产

Plasmid DNA (pDNA) is the starting point for the production of various next-generation biopharmaceuticals. 然而, pDNA molecules are larger and more sensitive than traditional modalities, creating a new set of manufacturing challenges
Explore the steps in a typical pDNA purification process
Understand the hurdles associated with efficient pDNA production, and discover how our solutions can help you overcome them

探索pDNA生产

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免费HEK293介质样品试剂盒

Sample media for gene therapy and viral vector vaccines

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Discover the ABL Europe’s New Viral Vector Production Facility

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Ambr 15® for High Throughput Upstream 过程 Development

A valuable tool for suspension adaptation of viral vector production cell lines, media development and viral vector screening.

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Ambr®250 Modular for Upstream 过程 Development and Optimization

A modular bioreactor system for rapid determination of critical parameters, i.e. timing of host cell line transfection or multiplicity of infection.

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Bioreactors and Fermenters from 100 mL up to 2,000 L.

生物抑制剂® STR for Cell Expansion and Viral Vectors Production

A single-use bioreactor family and an ideal platform for your flexible manufacturing facility supporting fed-batch and continuous processes.

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Sartobind® Membrane Chromatography for Viral Vectors 净化

A membrane adsorber technology ideally suited for the purification of viral vectors.

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Monoliths for Preparative and Analytical Chromatography

The right chromatography tools for the right tasks - and the skills to use them.

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Virus Counter for Rapid 病毒量化

A unique automated platform for real-time tracking of viral particles and quantification of total intact virus particles.

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咨询十大靠谱网赌平台的专家

咨询十大靠谱网赌平台的专家

Explore the Sartorius Platforms for Biomanufacturing

Vaccine Manufacturing, 过程 Development and Production

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再生医学

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Connect Upstream for Intensified Biomanufacturing

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